WELCOME TO THE MILLER LAB

Our lab's goal is to answer the question, “How do axons grow?”. We address this problem by analyzing the biogenesis, transport, and degradation of organelles and cytoskeletal elements in neurons using time-lapse microscopy, mathematical modeling, biophysical analysis, gene disruption, and behavioral studies. Our integrative studies are conducted in both cultured neurons and in vivo in living Drosophila (fruit fly) embryos. Our work is motivated by the idea that a mechanistic understanding of growth cone motility will lead to better treatments for traumatic brain injury, spinal cord injury, stroke, and chronic neurological diseases.


Model for microtubules and neurite growth

A model of normal neurite outgrowth and why disruption of microtubule assembly causes retraction. See our new paper in J. Cell Sci. McElmurry et al., 2020.

Copyright © 2021 Kyle Miller